Clonidine — role?
Centrally acting alpha2-agonist for hypertension.
Parasympatholytic drugs — effect?
Antagonize parasympathetic signaling, reduce secretions.
Beta-adrenergic receptors — effect?
Stimulation relaxes the uterus.
Antidopaminergic neuroleptics — adverse effect?
Extrapyramidal symptoms like pseudo-parkinsonism.
Pseudo-parkinsonian syndrome — cause?
Dopamine-blocking antipsychotics like haloperidol.
Benzodiazepines — primary action?
Enhance GABA neurotransmission, produce anxiolysis.
Clozapine — EPS risk?
Lower risk of extrapyramidal symptoms.
Metronidazole — interaction with alcohol?
Produces disulfiram-like reaction.
H. pylori regimen — components?
PPI + bismuth + metronidazole + tetracycline.
Liposomal amphotericin B — benefit?
Reduces nephrotoxicity.
Ertapenem — coverage?
Does not cover Pseudomonas aeruginosa.
Mannitol — use?
Reduce cerebral edema in brain injury.
Loop diuretics — site?
Loop of Henle.
Thiazide diuretics — site?
Distal tubule.
Acetazolamide — mechanism?
Inhibits carbonic anhydrase.
Partition constant — role?
Determines drug distribution between lipids and water.
Urinary ion trapping — effect?
Increases drug elimination by raising urine pH.
Therapeutic drug monitoring — drugs?
Antiepileptics, aminoglycosides, digitalis.
Digoxin — therapeutic range?
0.8 to 2 ng/mL.
HemoglobinA1c — purpose?
Assess long-term glycemic control.
Testez vos connaissances avec un QCM de 20 questions sur Pharmacology Essentials for Healthcare.
1. Which drug is a centrally acting alpha2-adrenergic agonist used for hypertension and opioid withdrawal treatment?
2. What is the expected effect of beta-adrenergic receptor stimulation on the uterus?
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