Flashcards : Understanding Adverse Drug Reactions and Susceptibility — 10 cartes

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1Question

ADR — definition?

Réponse

Unintended, harmful response at normal doses.

2Question

ADR — definition?

Réponse

Unintended, noxious response to drug at normal doses.

3Question

ADR & mechanism — role?

Réponse

Results from pharmacodynamic or pharmacokinetic factors.

4Question

Side Effect — difference?

Réponse

Related to pharmacology; can be beneficial, neutral, or harmful.

5Question

Side effects — properties?

Réponse

Related to drug's pharmacology; may be beneficial or neutral.

6Question

ADE — definition?

Réponse

Adverse outcome post-drug use; includes all ADRs.

7Question

Type A ADR — characteristics?

Réponse

Predictable, dose-dependent, common, preventable.

8Question

Type B ADR — characteristics?

Réponse

Unpredictable, not dose-dependent, often serious.

9Question

Factors influencing susceptibility?

Réponse

Age, gender, genetics, co-morbidities, polypharmacy.

10Question

Immunological reactions — example?

Réponse

Allergic reactions like rashes, anaphylaxis.

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1. What is an adverse drug reaction (ADR)?

2. According to the WHO definition, an adverse drug reaction (ADR) occurs under what conditions?

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